Tag: DOAC
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Analysis of Anticoagulant Use in Asian Populations: Empirical Data and Clinical Implications
Abstract The therapeutic landscape for venous thromboembolism (VTE) is complex, particularly in Asian populations where genetic and physiological nuances significantly influence the risk-benefit ratio of anticoagulant therapy. This review delves into empirical data surrounding the administration of anticoagulants, such as Heparin and direct oral anticoagulants (DOACs), in Asians, highlighting pharmacogenomic considerations, hemorrhagic risk assessments, and…
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The Evolution and Clinical Application of Direct Oral Anticoagulants (DOACs): A Paradigm Shift in Anticoagulation Therapy
Abstract The advent of Direct Oral Anticoagulants (DOACs) has revolutionized the management of thromboembolic disorders, presenting a significant paradigm shift from traditional Vitamin K Antagonists (VKAs), such as warfarin. Introduced into clinical practice in 2008 with the approval of Dabigatran by the U.S. Food and Drug Administration (FDA), DOACs have expanded the therapeutic arsenal, offering…